Tightjunction相关论文
Objective:To explore the effect of Tangshen Formula (TSF),a Chinese herbal medicine,on interstitial cells of Cajal (ICC)......
Chlorothalonil induces the intestinal epithelial barrier dysfunction in Caco-2 cell-based in vitro m
The widespread use of chlorothalonil (CTL) has caused environmental residues and food contami-nation.Although the intest......
Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mi
Clostridioides difficile infection (CDI) is a common infection of the gastrointestinal tract.Typically,20％-30％ of CDI pati......
Research on the Relationship between Thick Greasy Tongue Fur Formation and Vascular Endothelial Cell
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Orchestration of occludins, claudins, catenins and cadherins as players involved in maintenance of t
Although spermatozoa are formed during spermatogenesis in the testis, testicular spermatozoa are immature and cannot swi......
Effects of dietary protein sources and levels on intestinal barrier function of 21 days old weaned p
This experiment was conducted to determine the effects of dietary protein sources and levels in relation to intestinal b......
The impact of in vitro matured (IVM) bovine oocyte vitrification on embryo compaction and the ability to undergo success......
Surface charge triggered intestinal epithelial tight junction opening based on chitosan nanoparticle
Exogenous insulin is essential in treating diabetes mellitus,Normally exogenous insulin was first transported to the liv......
Effect of Ala-Gln on the localization and expression of tight junction(TJ)protein occludin of IPEC-1
The objective of the present study was to determine effects of dietary Ala-Gln supplementation on intestinal barrier per......
Impaired intestinal growth in newborn IUGR piglets is concomitant with glutamine deficiency and redu
Intestinal growth is impaired in newborn piglets that have experienced intrauterine growth restriction and remains at a ......
Glutamine improves permeability and tight junction protein in response to oxidative stress in pig in
The gastrointestinal epithelium plays an important role in maintaining the mucosa barrier function in various species in......
Neonates with low birth weight (LBW) show lower efficiency of nutrient utilization compared with normal birth weight (NB......
Objective Background Platinum-based chemotherapy can significantly prolong the survival period of non-squamous non-small......
We have demonstrated that bradykinin(BK)could increase the permeability of blood-tumor barrier(BTB)via down-regulating t......
The γ-secretase blocker reduces the permeability of the blood-brain barrier by decreasing the ubiqui
Aim: Cerebral ischemia/reperfusion injury induces alterations in many signaling pathways that underlie BBB disruption an......
Bradykinin down-regulating the expression levels of ZO-1, occludin and disrupting actin cytoskeleton
Objective Tight junction (TJ) is an important structural and functional basis of maintaining blood-brain barrier (BBB) i......
Background: The neuroprotective effects of neuroserpin (NSP) have been studied in both patients and animal models with c......
IFNγR expression on endothelial cells prevents brain inflammation by promoting blood-brain barrier f
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Effect of muscarinic acetylcholine receptor activation on paracellular pathway in submandibular glan
Paracellular pathway via tight junction is an important route for materials transport.However,whether muscarinic acetylc......
Research on the relationship between thick greasy tongue fur formation and vascular endothelial cell
Objective: To determine the relationship of thick greasy tongue fur formation and permeability of vascular endothelial c......
The crosstalk between nitrosative stress and cellular autophagy-lysosome process in endothelial cell
OBJECTIVE The present study was desighed to determine the causative links and precise correlations among nitrosative str......
TGF-β1 Modulates Formation and Function of Tight Junction and Expression of Cadherins in Cultured Ov
Ovarian surface epithelium (OSE) is the origin of epithelial ovarian tumours.During the transformation to tumour, OSE lo......
AIM2 contributes to the maintenance of intestinal integrity via Akt signal to protect against Salmon
Purpose: The mechanism regulating gastrointestinal epithelial barrier remains poorly understood.We herein demonstrate th......
The influence of pore insert on tight junctions between cerebral brain endothelial cells of adult ra
Objective: Blood-brain barrier(BBB)is the structural basis of the central nervous system to maintain a stable internal e......
Food emulsifier glycerin monostearate enhances phthalates’ male reproductive toxicity to rats follow
Human beings are inevitably exposed to ubiquitous phthalates(PEs)surroundings,and simultaneously ingesting a plenty of f......
Preeclampsia umbilical cord serum-induced changes in tight junction morphology and occludin expressi
Objective To investigate preeclampsia umbilical cord serum-induced changes in the morphology of tight junction and the e......
Effects of Tong-Qiao-Huo-Xue-Decoction on the Blood-Brain Barrier permeability and the expressions o
Ethnopharmacological relevance:Tong-Qiao-Huo-Xue-Decoction (TQHXD) is a classical prescription in traditional Chinese me......
Effect of Tong-qiao-huo-xue decoction on the expressions of related proteins of the blood-brain-barr
Aim of the study:To evaluate the effects of TQHXD on the Blood-Brain Barrier (BBB) permeability and the expressions of r......
Hepatitis C is a major cause of chronic hepatitis worldwide and current medical treatment options are limited.Interferon......
Improvement of Intestinal Absorption of Water-Soluble Macromolecules by Polyamines:Assessment of The
Purpose: The purpose of this research is to study the effects of three kinds of polyamines on the intestinal absorption ......
Docosahexaenoic acid effects on the disruption of epithelial barrier function through altering lipid
Recently tight junction (TJ) are considered as raft-like membrane compartments and represent a structural and functional......
Chromatin remodeler INO80 mediates trophectoderm permeability barrier to modulate morula-to-blastocy
Inositol requiring mutant 80 (INO80) is a chromatin remodeler that regulates pluripotency maintenance of embryonic stem ......
血脑屏障(BBB)存在于血液和脑之间，可选择性地阻止有害物质进入大脑，保持其内环境的稳定。近年来，体外BBB模型由于其高效、低耗、重复......
Gracilaria fisheri oligosaccharides ameliorate inflammation and colonic epithelial barrier dysfuncti
Objective:To investigate the effect of Gracilaria fisheri oligosaccharides(GFO)on inflammation and colonic epithelial ba......
Cldn7b deficiency impairs the formation of the otoliths and the normal function of inner ear in zebr
The zebrafish is an excellent model for studying the development and function of inner ear.Herein,we reported the ch......
Chlorogenic acid,a natural phenolic acid present in fruits and plants,provides beneficial effects for human health.T......
目的研究溃疡性结肠炎患者肠道紧密连接蛋白occludin、ZO-1的表达及其临床意义。方法收集2014年1月—2017年10月在中国医科大学附......
Expression of intestinal mucosa tight junctions claudin proteins and mRNA in patients with irritable
Objective:To investigate the changes of intestinal mucosa tight junctions(TJs)claudin-1,-3,-4 proteins and mRNA changes ......
非小细胞肺癌目前发病率及病死率均居恶性肿瘤的首位,即便早期患者也有相当一部分出现较早的肿瘤复发转移,直接导致生存率的下降.......
多肽和蛋白质类药物具有高效、低毒及药物间相互作用小的特性，使得它们越来越多地应用于临床。胃肠道在人体和外界之间形成了一个选......
密封蛋白（ Claudin）是细胞间紧密连接的骨架蛋白，参与维持紧密连接的各种功能，其异常表达可破坏上皮细胞及内皮细胞的结构，导致其功能严......
肺泡上皮直接与外界环境接触以进行气体交换，微小的上皮屏障的改变就可能增加肺部患某些疾病的敏感性。最近的研究已经把肺上皮屏障......
目的观察高氟暴露对人血管内皮细胞紧密连接胞质带状闭合蛋白1（ZO-1）表达的影响，并初步探讨其机制。方法体外培养人脐静脉血管内皮细......
目的探讨丁酸对SD大鼠肠黏膜屏障的作用情况，为防治坏死性小肠结肠炎等肠道疾病提供实验依据。方法以生后7 d(P7)的SD新生鼠为实验......
目的 观察癫(痫)持续状态(SE)后脑水肿及血脑屏障破坏的动态变化.方法 建立氯化锂-毛果芸香碱大鼠SE模型,成模后0、4、24和72 h分......
Postcoital Administration of Asoprisnil Inhibited Embryo Implantation and Disturbed Ultrastructure o
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目的研究高迁移率族蛋白B1（high mobility group box-1 protein, HMGB1）对人脐静脉内皮细胞屏障通透性的影响，以及普通肝素对HMGB1介......
Triptolide (TP),an active component of Tripterygium wilfbrdii Hook.f.(TWHF),has been widely used for centuries as a trad......
Genetic factors may be learnt from families with gene mutations that render nerve-injury sus-ceptibility even to ordinar......
Interleukin-6, desmosome and tight junction protein expression levels in reflux esophagitis-affected
背景：对加压素的中等剂量低在败血或在心脏的外科以后在 cathecholamine 依赖的 vasodilatory 吃惊的治疗被使用了。我们在心脏的外......
